Han Solo (Star Wars) was fluent in Galactic Basic Standard, Shyriiwook, Trader's argot, Rodese, Illodian, and Huttese.
Darth Vader (Star Wars) was fluent in Galactic Basic Standard and Huttese, and understood to a certain degree the verbal form of the droid language Binary. He was also fluent in the ancient Sith language.
Luke Skywalker (Star Wars) was fluent in a variety of languages such as Galactic Basic, Huttese, Jawa Trade language, Shyriiwook, and Yuzz, and he also claimed to know twelve other common languages
Growing up on a farm, Kyle Katarn (Star Wars) had found a brother of sorts in his father's custom-made labor droid, WeeGee. As a result, Katarn became one of the few Humans in the galaxy fluent in the electronic language of Binary or droidspeak.
Corran Horn (Star Wars) understood and comprehended the language of Binary, or droidspeak.
Revan (Star Wars) spoke and comprehended a variety of languages beyond his native Basic: Mando'a, Binary, Huttese, Shyriiwook, Selkath and that of the ancient Sith
Zakarisz Ghent (Star Wars) displayed an ability to understand the language of Binary, or droidspeak almost perfectly.
Jango Fett (Star Wars) was fluent in Basic, Huttese, and Mando'a. He was also able to read Aurebesh, Mandalorian.
C-3PO (Star Wars) is fluent in over six million forms of communication.