- "Okay boys and girls, here are the rules. Find a penny, pick it up. Double it, you've got two pennies. Double it again: four. Double it 27 more times, and you've got a million dollars and the IRS all over your ass. Round and round and round it goes, where it stops nobody knows, but it all adds up... quick... It eats the whole universe, a monumental black hole, a giant whirling headstone marking the spot where we all used to live and play and slaughter the innocent."
- ― John Crichton explaining the Wormhole Weapon (Farscape)
- Cosmos Killer
- Universal Bust/Buster/Busting
- Universal Destruction
- Universe Destroying
The user can destroy an entire universe.
- May be limited to a certain size or category of universes.
- Can be reversed by Universal Recreation and Absolute Restoration.
- May be destroyed along with the Universe.
- Wormhole Weapon (Farscape)
- Ultimate Nullifier (Marvel Comics)
- Forever Crystal (Marvel Comics)
- The Anihilaarg (Ben 10: Omniverse)
- Omnitrix (Ben 10 franchise); after charging up in self-destruct mode for a few days
- Crest of Annihilation (Star Ocean)