- Universal Bust/Buster/Busting
- Universal Destruction
- Universe Destroying
The user can destroy an entire universe.
- May be limited to a certain size or category of universes.
- Can be reversed by Universal Recreation and Absolute Restoration.
- Wormhole Weapon (Farscape)
- Ultimate Nullifier (Marvel Comics)
- Forever Crystal (Marvel Comics)
- The Anihilaarg (Ben 10: Omniverse)
- Omnitrix (Ben 10 franchise); after charging up in self-destruct mode for a few days
- Crest of Annihilation (Star Ocean)