Users of the ability have achieved the highest level of combat proficiency (armed and unarmed) and are capable of performing superhuman/supernatural feats beyond normal boundaries. Masters of this ability have acquired a state of mental, physical, and spiritual balance, making them capable of defeating enemies only with their mere presence. Their combat skills are completely unmatched by anyone who came before or who will come afterwards, making them one of the most powerful opponents and a force to be reckoned with.
Yachiru Unohana (Bleach) has mastered all the countless sword styles in the world, becoming the first Kenpachi.
Acnologia (Fairy Tail) who is considered the King of Dragons possess ludicrous power that he is greater than the entire formidable armies of Alvarez and Ishgar and the mighty Wizard Saints and the dreaded Spriggan 12
Isaac Netero (Hunter × Hunter) is one of the strongest characters of the series and an extremely powerful practitioner of Nen.
Madara Uchiha (Naruto) was one of the most gifted shinobi in history. His skills in armed and unarmed combat allowed him to disarm and dispatch multiple ninja at once.
Dracule Mihawk (One Piece) is the strongest swordsman in the world. His skills in swordsmanship are great to the point where he is able to overpowering even Zoro with a mere dagger.
The Guardian (Samurai Jack) has countless eons of experience, and is the ultimate fighter, having beaten and nearly killing Jack with little effort.
Sigrun (Valkyrie Crusade) as the goddess of battle, has absolute combat skills.
Shinobu Sensui (Yu Yu Hakusho) is an incredibly powerful human who mastered the Resshūken, an elegant fighting style that is only available to fighters that have mastered all other forms of martial arts. He also mastered the Sacred Energy, the highest echelon of power that even Genkai couldn't achieve.
Raizen (Yu Yu Hakusho) was a Mazoku, an immensely powerful demon warrior, that even starving himself for centuries and merely using his descendant, Yusuke Urameshi, as a temporary medium he was able to decimate the mighty Sensui.
Ryu Hayabua (Ninja Gaiden series) has been stated to be the most powerful ninja in the world. His skills in combat, weaponry, and spiritual practices have allowed to challenge and defeat military soliders and machines, biological expirments, and fiends and deities of the highest class.
Being of godly-status and having mastery in over 700 distinct fighting styles involving both armed and unarmed combat makes Raiden (Mortal Kombat) one of the most deadliest adversaries to come across of his Universe and perhaps the most versatile.
Meliodas (Nanatsu no Taizai) In the past was considered to be one of the most callous of the Demon Clan and the former leader of the Ten Commandments. Feared by even the Goddess Clan for his monstrous power, combat and sword skills. Being considered the only one worthy of the position of Demon King.