The user is or can use the abilities of transcendent aliens, whose powers are so advanced that they can be confused with Deities by lesser creatures. Such aliens are often said to have influenced evolution on countless worlds and may or may not be the first and most advanced sentient species in the universe. Sometimes they can even go beyond their universe, becoming multiversal beings.
Celestialsapiens (Ben 10) are extra dimensional aliens with vast cosmological and reality alternating powers.
Pyron (Darkstalkers) has evolved into a godlike entity over millions of years.
Superman-Prime (DC One Million) is the original Superman, having evolved over the millennia into a godlike being.
After harnessing the power of six pure-hearted Saiyans, Goku (Dragon Ball Z) became the legendary Super Saiyan God.
After becoming Super Saiyan Gods and mastering the power, Goku and Vegeta (Dragon Ball Z) ascended to become Super Saiyan Blue.
The Ori (Stargate Franchise), as ascended beings, wield cosmic powers and immense knowledge of the universe
The FAR/First Ancestral Race (Neon Genesis Evangelion) are the ancient precursor race ultimately responsible for the existence of both the angels and humans, and capable of a level of technology beyond any hope of understanding.
Alien Maxwell (Valkyrie Crusade) is an alien goddess. she is also known as the Dark Empress because of her dreadful power.
Alien Ildanach (Valkyrie Crusade) is an almighty alien sun deity.