- "Total event collapse! Every sun will supernova at every moment in history! The whole universe will never have existed! Please! Listen to me!"
- ― The Doctor (The Pandorica Opens)
- ""Smooth move Space Lax! You've destroyed the totality of existence!"-Kodos "Its ok, I'll leave a note."-Kang"
- ― Treehouse of Horror XVI Opening (The Simpsons)
- Reality Destruction
- The Great Collapse
- Total Collapse
User can destroy every single object in a universe, the universe itself, and every parallel universe, alternate dimension, plane of existence, possible universe, impossible world, divergent timeline, alternate continuity, and reality, effectively annihilating all of creation, even up to destroying the very origin of the verse/series franchise, effectively undoing the very act of creation itself.
- Dimension Destruction
- Reality Sundering
- Space Depletion
- Time Destruction
- Universe Destruction/Multiverse Destruction/Omniverse Destruction
- The user may not be immune and could destroy themselves.
- May have to channel a enormous amount of energy to use this ability.
- Users of Omnilock are immune
- Users of Absolute Restoration can undo the destruction.
- Accela-Ray (The Simpsons)
- SCP-001-The Button (SCP Foundation)
- Super Hulkhider (Space Dandy)
- Choedan Kal (Wheel of Time); if used at full power
- Anihilaarg (Ben 10: Omniverse); via combining with the Dwarf Star
- Chronosapien Time Bomb (Ben 10: Omniverse)