Buffy (Buffy the Vampire Slayer) can detect vampires within her area.
Buffy Summers (Buffy the Vampire Slayer) senses Spike hiding behind a tree and pulls him into the open.
Blade (Marvel Comics) can sense supernatural activity.
D (Vampire Hunter D)
Grimms (Grimm) are able to see the true form of Wesen even when the Wesen don't want them to
Danny Fenton's (Danny Phantom) Ghost Sense alerts him to the presence of ghosts other than himself, usually manifesting as a blue mist.
Cole MacGrath (Infamous 2: Festival of Blood) using Vampire Sense to discover a disguised vampire.
Lydia Martin and Meredith Walker (Teen Wolf) are able to sense every supernatural creature in Beacon Hills; Meredith put these beings on the Deadpool hit-list, whereas Lydia made a list for her mother to help protect her.