Kei and Yumi (Ape Escape 3), when morphed as the Fantasy Knight, posses immense strength with their weapons that allows them to break the armor of monkeys.
Whenever Kei and Yumi morph into the Cyber Ace, they are able to project powerful laser that is able to blasts of the armor of the stronger monkeys.
Using the Shock Gloves, Batman (Batman: Arkham Origins) can effortlessly pierce through riot shields and body armor.
Ichigo Kurosaki's (Bleach) Bankai is so powerful, that simply releasing it caused Yukio's Chatroom dimensional barrier to split and shatter, which shouldn't be possible by normal means.
Gabriel Belmont/Dracula (Castlevania: Lords of Shadow) can use his Chaos Claws to penetrate enemy shields and armor through brute force and heat.
Piccolo (Dragon Ball) piercing through Babidi's Wizard Barrier.
Lucina's (Fire Emblem/Super Smash Bros.) Shield Breaker attack can easily pierce through enemy shields when fully charged.
When his Blades of Athena are infused with Thera's Bane, Kratos (God of War series) is able to destroy the shields and armors of various creatures, and even and damage with armored skin of Thantos' beast form.
Voldemort (Harry Potter) uses the Elder Wand to penetrate the shield around Hogwarts.
Inuyasha (InuYasha) can use the Diamond Tessaiga's Adamant Barrage technique to penetrate barriers that the Red Tessaiga cannot.
Naraku (InuYasha) using the Yōmeiju's branches to dissolve the Infant's barrier.
Whenever Jak (Jak and Daxter: The Precursor Legacy) is empowered with either Red or Yellow eco, he is able to easily dispatch of bone armor Lurkers and the shields of Lurker glacier troops in one hit.
The Zeekeeper (Mario & Luigi: Dream Team) fires his Wakebeam to penetrate the barrier around Neo Bowser Castle.
Sasuke's (Naruto series) Chidori is powerful jutsu that is well known for penetrative capabilites. It is strong enough to pierce through Gaara's otherwise impenetrable sand-based defense.
Whenever he becomes Super Sonic, Sonic (Sonic The Hedgehog series) is powerful enough to break through powerful barriers.
After acquiring a full-powered Master Sword, Link (The Legend of Zelda: The Wind Waker) was able to destroy the magic barrier around the Hyrule Castle created by Ganondorf.
Using the Fused Shadow, Midna (The Legend of Zelda: Twilight Princess) was able to destroy the magic barrier Ganondorf placed around Hyrule Castle.
Renesmee Cullen (Twilight) can penetrate both mental and physical shields via touch.
Although it is a Rank C technique, Hiei (Yu Yu Hakusho) was able to use the Sword of the Darkness Flame to slash and burn through Kuro Momotaro's Armor of the Wolf.
Zatch Bell and Kiyo (Zatch Bell!) can use Zakeruga to fire a concentrated beam of lightning with the force to pierce armor.
Randgrith (Valkyrie Crusade) the Shield-Destroyer.
The Liger Zero (Zoids) is one of the Zoids that posses the Strike Laser Claw, a chargable energy weapon that is powerful enough to tear through enemy armor to deal damage.