The Lantern Rings (DC Comics)
The Infinity Gems (Marvel Comics)
Infinity Gauntlet (Marvel Comics)
The symbiote (Marvel Comics) which gave Venom and Carnage their powers.
The Mask of Loki (The Mask, & Son of the Mask)
Ichigo (Bleach) uses a manifested shinigami blade of his powers.
While wearing the mask, Ichigo's (Bleach) Hollow powers supplement his Shinigami powers, giving him a vast increase in strength, speed, durability and spiritual power, including augmented his Getsuga Tenshō.
Grimmjow Jaegerjaquez (Bleach) using the Caja Negación cube to create a pocket dimension field to imprison Ulquiorra Cifer.
Yukio (Bleach) using his Fullbring ability via his game console to create a pocket dimension.
When the Visoreds put on their Hollow Masks their power augmented, increasing their strength, speed, and durability, some are equipped to fire a Cero like Hollows.
When Kaname puts on his Hollow Mask, his strength and speed increase and develops high-speed regeneration.
D.R. (Monsters) wielding the Dragon Horn, which allows him to summon and control dragons.
The Devil Fruit (One Piece)
Pandora's Box (Code:Breaker)
The Philosophers Stone (Fullmatel Alchemist: Brotherhood)
Tetsusaiga and Tenseiga (InuYasha)
The Artifacts of Darkness (Yu Yu Hakusho): Orb of Baast, Forlorn Hope and Shadow Sword.
Sailor Moon (Sailor Moon) with the Silver Crystal
Reiki, in the hands of a special power user, can negate all special powers.
The armor, Eternity, and sword, Instant grants eternal life and deflection of attacks (Pokemon Manga).
Elder Wand (Harry Potter)
Zelena (Once Upon a Time) loses her power after her pendant is removed.
Oz Pendants (Once Upon a Time)
Rings of the Planeteers (Captain Planet)
Talismans (The Adventures of Jackie Chan)
Shen Gong Wu (Xiaolin Showdown)
Elements of Harmony (My Little Pony: Friendship is Magic)
Alicorn Amulet (My Little Pony: Friendship is Magic)
Omega-1 Nanite (Generator Rex)
Meta-Nanites (Generator Rex)
The Omnitrix (Ben 10 series)
Reality Gauntlet (Danny Phantom)
Miraculouses (Miraculous: Tales of Ladybug & Cat Noir) are magical pieces of jewelry powered by sprite-like beings called kwami, granting the wearers various abilities and a super alter-ego.
The Sword of Sparda (Devil May Cry)
The Kingdom Key (Kingdom Hearts)
Apples of Eden (Assassins Creed)
The Blades of Exile (God of War)
The Blades of Chaos (God of War)
The Blade of Olympus (God of War) was a powerful weapon that Zeus forged from the heavens and the earth.
Elemental Stones (Bomberman 64: The Second Attack)
Bomb Elements (Bomberman Generation)
Chaos Emeralds (Sonic the Hedgehog)
Master Emerald (Sonic the Hedgehog)
Sol Emeralds (Sonic the Hedgehog)
Worlds Ring (Sonic the Hedgehog)
Sonic's shoes (Sonic the Hedgehog)
Chaos Crystals (Sonic Boom)
The Master Sword (The Legend of Zelda)
The Magic Armor (The Legend of Zelda: The Wind Wake) grants an invincible defense.
The Magic Armor (The Legend of Zelda: Twilight Princess) makes the wearer invincible.
The Rod of Seasons allows Link to change the very four seasons.
The Harp of Ages allows Link to warp through time itself.
The Phantom Sword (The Legend of Zelda: Phantom Hourglass)
The Lokomo Sword (The Legend of Zelda: Spirit Tracks)
The Goddess Sword (The Legend of Zelda: Skyward Sword)
The Star Rod (Mario/Kirby)
The Mega Stones and Key Stone (Pokemon) can be used to make a specific pokemon Mega Evolve.
By holding a Z-Ring and a specific Z-Crystal (Pokemon) a trainer can make his pokemon use a powerful Z-Move.
The Ray-Sphere (inFAMOUS)
Holy Cross from (Dante's Inferno)
Death's Scythe from (Dante's Inferno)
Necronomicon Ex-Mortis, the Book of the Dead (Evil Dead)
BHB's Gravity Generator (Bomberman 64: The Second Attack)
The Guru uses the Moon Stone he holds to use his mystical powers.
Kazuma's Shell Bullet fins (S-cry-ed).
Jewel Girl (Valkyrie Crusade) can gain a specific power from each jewel (Black Pearl: Exorcism. Hematite: Victory Inducement. etc)
Power Rings of Inspiron (Air Buddies)
Malachite's Hand (Channel Awesome) was a powerful artifact that grants the user limitless magical power. Because the original gauntlet was old and unfashionable, the stone that powers it was grafted onto a Nintendo Power Glove.
Aeon (Channel Awesome - Suburban Knights) crafted a ring made from lodestone that could reflect Malachite's magic back to him.