The Sword of Sparda (Devil May Cry)
The Kingdom Key (Kingdom Hearts)
The Black Lantern Ring (DC)
The White Lantern Ring (DC)
The Green Lantern Ring (DC)
The Blue Lantern Ring (DC)
The Indigo Lantern Ring (DC)
The Violet Lantern Ring (DC)
The Yellow Lantern Ring (DC)
The Orange Lantern Ring (DC)
The Red Lantern Ring (DC)
The Infinity Gems (Marvel)
The Mask of Loki (The Mask, & Son of the Mask)
Ichigo (Bleach) uses a manifested shinigami blade of his powers.
D.R. (Monsters) wielding the Dragon Horn, which allows him to summon and control dragons.
The Devil Fruit (One Piece)
Pandora's Box (Code:Breaker)
The Philosophers Stone (Fullmatel Alchemist: Brotherhood)
The symbiote (Marvel) which gave Venom and Carnage their powers
Apples of Eden (Assassins Creed)
The Blades of Exile (God of War)
The Blades of Chaos (God of War)
The Artifacts of Darkness (Yu Yu Hakusho): Orb of Baast, Forlorn Hope and Shadow Sword.
Talismans (The Adventures of Jackie Chan)
Shen Gong Wu (Xiaolin Showdown)
Elder Wand (Harry Potter)
Elemental Stones (Bomberman 64: The Second Attack)
Bomb Elements (Bomberman Generation)
Elements of Harmony (My Little Pony: Friendship Is Magic)
Alicorn Amulet (My Little Pony: Friendship Is Magic)
Chaos Emeralds (Sonic the Hedgehog)
Master Emerald (Sonic the Hedgehog)
Sol Emeralds (Sonic the Hedgehog)
Worlds Ring (Sonic the Hedgehog)
Sonic's shoes (Sonic the Hedgehog)
Chaos Crystals (Sonic Boom)
The Blade of Olympus (God of War) was a powerful weapon that Zeus forged from the heavens and the earth.
The armor, Eternity, and sword, Instant grants eternal life and deflection of attacks.
The Master Sword (The Legend of Zelda)
The Magic Armor (The Legend of Zelda: The Wind Wake) grants an invincible defense.
The Magic Armor (The Legend of Zelda: Twilight Princess) makes the wearer invincible.
The Rod of Seasons allows Link to change the very four seasons.
The Harp of Ages allows Link to warp through time itself.
The Phantom Sword (The Legend of Zelda: Phantom Hourglass)
The Lokomo Sword (The Legend of Zelda: Spirit Tracks)
The Goddess Sword (The Legend of Zelda: Skyward Sword)
Tetsusaiga and Tenseiga (InuYasha)
The Star Rod. (Mario/Kirby)
Omega-1 Nanite (Generator Rex)
The Omnitrix. (Ben 10 series)
The Ray-Sphere. (inFAMOUS)
Holy Cross from (Dante's Inferno)
Death's Scythe from (Dante's Inferno)
Rings of the Planeteers (Captain Planet)
When the Visoreds put on their Hollow Masks their power augmented, increasing their strength, speed, and durability, some are equipped to fire a Cero like Hollows.
When Kaname puts on his Hollow Mask, his strength and speed increase and develops high-speed regeneration.
Necronomicon Ex-Mortis, the Book of the Dead (Evil Dead)
BHB's Gravity Generator (Bomberman 64: The Second Attack)
Reiki, in the hands of a special power user, can negate all special powers.
The Guru uses the Moon Stone he holds to use his mystical powers.
Sailor Moon (Sailor Moon) with the Silver Crystal
Zelena (Once Upon a Time) loses her power after her pendant is removed.
Kazuma's Shell Bullet fins (S-cry-ed).
Jewel Girl (Valkyrie Crusade) can gain a specific power from each jewel (Black Pearl:Exorcism.Hematite:Victory Inducement.etc)
Power Rings of Inspiron (Air Buddies)
While wearing the mask, Ichigo's Hollow powers supplement his Shinigami powers, giving him a vast increase in strength, speed, durability and spiritual power, including augmented his Getsuga Tenshō.
Grimmjow Jaegerjaquez (Bleach) using the Caja Negación cube to create a pocket dimension field to imprison Ulquiorra Cifer.
Yukio (Bleach) using his Fullbring ability via his game console to create a pocket dimension.