The user can put their power into overdrive boosting their ability way beyond their limit making it stronger or ignore it weakness. Sometime gaining a sudden boost of stamina, strength, speed and endurance in the process of using the power.
It must be a power that they already have but boosted beyond their limits or so-called limitations at the cost of losing it. After use, the user will lose their powers, either permanently or temporarily.
The user loses all powers, ability and physical ability after use.
Issei Hyoudou (Highschool DxD); via complete Juggernaut Drive
Gon Freecss (Hunter x Hunter)
Ichigo Kurosaki (Bleach); after using Final Getsuga Tenshō
Quincies (Bleach); via "Quincy: Letzt Stil"
Sajin Komamura (Bleach); via Humanization Technique
Natsu Dragneel (Fairy Tail); using more Magic than capable for years
Sherri Blendi (Fairy Tail); via Third Origin
Users of Overtrance (Luck and Logic)
Kazuki Shikimori (Maburaho); via using his magic
Franklin Richards (Marvel Comicsl); when reviving Galactus
Valeria Richards (Marvel Comics); when reviving Galactus
Anti-Venom (Marvel Comics); when curing the mutated victims from the "Spider-Island" incident
Kagero (Naruto); via Ephemeral
Ryoma Echizen (Prince of Tennis); via Pinnacle of Perfection
Spyro (The Legend of Spyro)
Superman (DC Comics); via Super Flare
Lestion (Yumekui Merry); via firing his gun
Ophis's Snakes (Highschool DxD)
Uryu Ishida (Bleach) using Quincy: Letzt Stil to boost his strength, as the cost of his powers after the brief moment.
Natsu Dragneel (Fairy Tail) has always been using more magic than his body can supply, leading to him to developing a Anti-Magic Tumor.
After using the Convexity Fury to defeat and purify Dark Cynder, Spyro (The Legend of Spyro) lost all of his elemental powers, forcing him to relearn them with help from the Chronicler.
Ichigo Kurosaki's (Bleach) Final Getsuga Tenshō allows him to transcend the limits of both Shinigami and Hollow, but will deprive him of his powers after use.
Superman (DC Comics) uses the Super Flare to expel all of the solar energy in his cells in the form of a massive explosion that incinerates everything within a quarter-mile radius, at the cost of him losing his powers for the next 24 hours.
Lestion (Yumekui Merry) can kill any dream demon with his gun, but doing so will destroy him and shatter his vessels conscious and subconscious minds in the process.