Haru Glory's (Rave Master) special power, Rave, is connected to his shape shifting sword, Ten Commandments.
He-Man (Masters of The Universe) possesses the virtually indestructible Power Sword.
Lion-O (ThunderCats) wields the Sword of Omens, a legendary treasure and cultural treasure of the Thundercats.
The Trap Team (Skylanders) wield powerful weapons made out of magical Traptanium crystals.
As a powerful Umbran Witch Bayonetta (Bayonetta) can access Rodin's colorful gallery of hellish super weapons created from the Angelic Hymns Golden LP's to aid herself in the survival battles against the relentless onslaught of heavens legions, tools with which she can harmonize her wicked weaves and demonic summons in unison for the slaughter of said assailants in impeccable style.
Augus (Asura's Wrath) wields the mystical sword, Wailing Dark, which can project energy waves and extend to seemingly endless lengths.
During his adventures in the time of King Arthur, Sonic (Sonic The Hedgehog series) wielded the talking sword, Caliburn, which is actually the greatest of the Sacred Swords, Excalibur.
Sora (Kingdom Hearts) is one of many who are chosen to wield the sacred Keyblade in the battle of darkness and light.
Ch'rell/Shredder (Teenage Mutant Ninja Turtles) had sword smiths craft the blade from utrom metal placed it on a handle to electrify it, thus creating the Sword of Tengu, which he used to conquer Japan. According to Master Splinter, the sword is a potent mix of science and sorcery. The sword is capable of producing powerful sonic waves, allowing it to destroy anything in its path and redirecting the attacks of the Mystic Foot Ninjas.
The Sword of Tengu (Teenage Mutant Ninja Turtles) is so powerful that not just anyone can wield it. The only two possible ways that anyone can wield the sword is they wear a special kind of protective armor (Much like Ch'rell in his Shredder exo-suit) or if someone is a true Ninjutsu master, but even then user can only wield it for a short time without burning their hands.
Kratos (God of War series) is highly proficient multiple forms of weaponry. He has either acquired or stolen various weapons from gods and powerful beings which are capable of manipulating the forces of nature and magic.
Hervor (Valkyrie Crusade) wields the magic sword Tyrhung.
Gunner (Valkyrie Crusade) wields two magical handheld water guns.
Dainsleif (Valkyrie Crusade) wields the magic sword Dainsleif.
Azrael/Michael Lane (DC Comics) duel-wields the Sword of Sin and the Sword of Salvation.
Wario (Stupid Mario Brothers) wielding the Nether Saber, an ancient Beam Sword created by Merlin. The Nether Saber is so powerful that its wielder is guaranteed to win every battle.
The Darkness (Stupid Mario Brothers) wielding the Black Widow Blade, a Beam Sword of pure evil created by Nox Decious.
The Monado (Xenoblade Chronicles) is a powerful mystical weapon that can manipulate the ether around it and grant the wielder access to special "Arts."
Jack (Samurai Jack) wields a magical katana forged by the gods Odin, Ra, and Vishnu.
This knife (Supernatural), mystical weapon forged by the Kurdish people, able to kill most demons and hellhounds with a single stab to a vital area.
The Colt (Supernatural), supernatural revolver that can kill all but five supernatural creatures with a single bullet.
The Metal Vessels (Magi the Labyrinth of Magic) are seventy-two magical treasures of immense power empowered by Solomon's Djinns, each of them have enough power to destroy the world...
...including Sinbad Metal Vessel empowered by the Lightning Djinn Baal...
...Alibaba's Metal Vessel empowered by the Fire Djinn Amon...
...Kogyoku's Metal Vessel empowered by the Water Djinn Vinea...
...Kouha 's metal vessel empowered by the Strength Djinn Leraje...
...Kouen's Metal Vessel empowered by the Gravity Djinn Agares...
...Hakuryuu's Metal Vessel empowered by the Life Djinn Belial.