The user is an animal or other nonhuman being who takes on or has the form, traits and abilities of humans, allowing them to take a human shape, prehensile hands, or do social activities such as whistling, playing sports or doing acrobatics, and also enables the user to speak the language of humans.
This also allows them to become bipedal, either digitigrade or plantigrade, however, this only applies to animals who are quadrupedal.
Various anthropomorphic australian animals (Crash Bandicoot)
Dante and Virgil (Devil May Cry) are the sons of a demon father and human mother, giving them human attributes and traits such as physical appearances like any other human, but no human limitations due to there demon heritage.
Various anthropomorphic asian animals (Legend of Kay)
Various characters (Morenatsu)
Various anthropomorphic animals (Sly Cooper)
Cats and dogs (Solatorobo: Red the Hunter)
Various anthropomorphic animals (Sonic the Hedgehog)
Inklings (Splatoon) possess both squid and human traits.
Agent 3 (Splatoon)
The Squid Sisters (Splatoon), Callie (left) and Marie (right)
Cap'n Cuttlefish (Splatoon)
DJ Octavio (Splatoon), like all Octarians, possesses both octopus and human traits.
Annie (Splatoon, the sea anemone) and Moe (the clownfish)...
...and Spyke (the sea urchin) are all non-human animals with human-like qualities.
Anthropomorphic animals (Star Fox)
Various anthropomorphic australian animals (Ty the Tasmanian Tiger)