"We're mutants. Born different from baseline humanity, with an enhanced genome that gives us super-powers. You piss us off at your peril."
― Shadowcat (Marvel Comics)

The power to be a human that possesses various supernatural abilities and powers while retaining one's humanity. Mutated version of Human Physiology. Not to be confused with Mutated Physiology.

Also Called

  • Enhanced Human Physiology
  • Evolved Humans/Evos (Heroes)
  • High Humans (The New Gate)
  • Homo Sapiens Mutandis/Mutantis (Marvel Comics)
  • Homo Sapiens Superior Physiology
  • Homo Superius Physiology
  • Human Mutant Physiology
  • Metahuman/Superhuman Physiology
  • Neohuman Physiology
  • Superpowered Human Physiology


User is a human being that has developed powers and abilities from a variety of causes, such as evolution, genetic experiments, enchantment, having powers bestowed upon them by other beings or sources, through birth, and training in order to obtain said powers.

Also, thanks to the human side of their heritage (if the powers are genetically-based), they are able to use these abilities without becoming a monster (i.e. keeping their human physique, sanity, and humanity without it being altered from possible instability).

Depending on the amount of powers they possess, especially regarding resistance/immunity, etc, Metahumans can be much stronger and more powerful than regular Humans in the long run. For example, they could survive environments that would be otherwise dangerous to normal Humans, they can defeat threats that regular to peak Humans couldn't fight back, and can even handle occupations to a much better intuitive standard, as well as acquiring better skills that normal to peak Humans could never hope to reach.

Homo Superiors can also be divided into two categories:


Metahumans of this category gain their powers via evolution, birth, genetic engineering, or exposed to radiation or biohazardous substances, like mutagens, or any other methods that involves genetic experimentation in that regard.
In one way or another, certain Homo Superiors that are of this classification will may have minor physical changes without their humanity being fully or almost slipped away, like their irises changing to any color like a fiery shade of red, yellow, purple, etc, retractable claws or spikes, fangs or sharp teeth, color of the skin being changed, among others. In fact, these kinds of Superhumans will be able to possess powers without their physiology being altered and lose their humanity as a result.


Non-Genetic Metahumans gain their powers whether they have abilities bestowed upon them by supernatural beings, enchantment, training to bestow powers like Telekinesis for example, being blessed or granted wishes to obtain powers, and among any other methods without any genetic tinkering. Unlike genetic-based Homo Superiors this category of Metahumans wouldn't have to be able to suffer mutations and instability of their Deoxyribonucleic Acid, which can be caused in certain ways. Just because Superhumans are of this category, doesn't necessarily mean they are any weaker than genetic-based Metahumans.

Applications (General)

Applications (Detail)

Powers that users may possess, but are not limited to:




  • Unless they have specific immunities/resistances, users have the same weaknesses as regular Humans.
  • Genetic-based abilities may become unstable and cause secondary/unwanted mutations.

Known Users


  • Alex Mann/Action Man (Action Man 2000)
  • Dr. Wolfgang Greenholtz/Professor Gangrene (Action Man 2000)
  • Templeton Storm/Tempest (Action Man 2000)
  • K.O. (OK K.O.! Let's Be Heroes)
  • Benders (Avatar Series)
  • Superhumans (Ben 10 Series)
  • Metahumans (DCAU)
  • Metahumans (Dexter's Laboratory)
  • Human E.V.O.s (Generator Rex)
  • The Powerpuff Girls (The Powerpuff Girls)
  • Team Go (Kim Possible)
  • The Rainbooms (My Little Pony Equestria Girls Series)
  • Trina Riffin (Grojband)



  • Carrie White (Carrie Series)
  • Andrew Detmer (Chronicle)
  • Matt Garetty (Chronicle)
  • Steve Montgomery (Chronicle)
  • David Rice (Jumper)
  • Griffin O'Conner (Jumper)
  • Supers (The Incredibles)
  • Enhanced Humans (Marvel Cinematic Universe)
  • Peculiar Children (Miss Peregrine's Home For Peculiar Children)
  • Alice/Janus Prospero (Resident Evil Movie Series)
  • Thomas A. Anderson/Neo (The Matrix Series)
  • Human Force Sensitives (Star Wars)


  • Neohumans (The Young Guardians)
  • Matilda Wormwood (Matilda)
  • Metahumans (Meta)
  • Supers (The First Superhero)
  • Empowered (ONSET)
  • ULTRAs (The Last Hero)
  • Superhumans (The New Heroes)
  • Prodigies (Renegades)

Live Television

  • Metahumans (Arrowverse)
  • Alphas (Alphas)
  • Evolved Humans/Evos (Heroes)
  • Meteor Infected (Smallville); via Kryptonite Meteors
  • Metahumans (Smallville)
  • Jim Ellison (The Sentinel)
  • Homo Superior/Evolved Humans (The Tomorrow People)
  • Human Augments (Star Trek series)


  • Ajins (Ajin)
  • Altered (Area D)
  • Contractors (Darker than Black)
  • Titan Shifters (Attack On Titan)
  • Fullbringers (Bleach)
  • Ryohei Sasawaga (Katekyo Hitman Reborn)
  • Shinobi/Kunoichi (Naruto)
  • Deadmen (Deadman Wonderland)
  • Superhumans (Dragon Ball series)
  • Various Characters (Charlotte)
  • Various Characters (Inou Battle wa Nichijou kei no Naka de)
  • Various Characters (Sagrada Reset)
  • Quirk-Users (My Hero Academia)
  • High Humans (The New Gate)
  • The Vinsmoke Siblings (One Piece)
  • Various Characters (One-Punch Man)
  • Shinichi Izumi (Parastye); after fusing with Migi’s cells
  • Alter Users (s-CRY-ed)
  • Espers (Mob Psycho 100)
  • Espers (A Certain Magical Index)
  • Espers (Akira)
  • NEXT (Tiger and Bunny)
  • Players (Darwin's Game)


Video Games

  • Conduits (inFAMOUS)
  • Max Caulfield (Life is Strange)
  • Human Biotics (Mass Effect Series)
  • Evolved (Prototype)
  • Gabriel Reyes/Reaper (Overwatch)
  • Lena Oxton/Tracer (Overwatch)
  • Sherry Birkin (Resident Evil series)
  • Albert Wesker (Resident Evil series); formerly
  • Alexia Ashford (Resident Evil series); formerly
  • Body Guard (Valkyrie Crusade)
  • Homo nintendonus (Super Mario Bros.)







Live Television


Video Games