Even without her Power Suit, Samus Aran's (Metroid) infusion with Chozo blood and extensive training have made her a "super athlete" with speed and agility that no normal human could hope to match.
Due to keeping his physical abilities at their peak, Uryū can easily hold out against all but the most resilient opponents during a battle.
Yuffie Kisaragi (Compilation of Final Fantasy VII)
Mike's female persona, Svetlana, proclaims herself to be Olympic queen of gymnastics.
Sly Cooper skills include parkour, gymnastics and acrobatics.
Carmelita's acrobatic skills are capable of matching Sly in agility and speed.
Kendra (Buffy the Vampire Slayer) comes to the rescue.
Sara Spencer (Dinosaucers) is already athletic, but with her Secret Scouts Ring, she can strongly boost her physical abilities a little more than that of an Olympic athlete, allowing her to jump at amazing heights, run faster, and be more agile.