The circumstance in which the user is dependent on the regular usage of drugs, devices, etc. to control/retain their powers, stay cognizant, or even to remain alive. Variation of both Affinity and Aversion. Opposite to Self Sufficiency and Self-Sustenance
The user is forced to regularly use something, such as drugs, devices, species, structures, elements, etc. to perform certain tasks in order, remain alive and/or to retain/control their powers.
Quarians (Mass Effect) are dependent on specialized environmental suits because of their near-nonexistent immune systems.
After losing his body's ability to regulate temperature, Python (Metal Gear Solid: Portable Ops) must wear a special cooling suit filled with liquid nitrogen or risk being literally burned alive from the inside out.
Albert Wesker (Resident Evil) needs to regularly inject himself with a specialized serum to keep the virus inside his body in check.
Drahmin (Mortal Kombat) needs to wear the Face of Kun-Lo to prevent himself from losing his mind to an oni's mindless rage.
Raziel (Legacy of Kain) must regularly consume souls to maintain his physical body or risk being shunted back to the Spectral Realm.
Due in part to their severe psychological trauma, the members of the Beauty and the Beast Unit can only survive outside of their suits for a few minutes.
After suffering irreparable damage to his heart and lungs, Dingo Egret (Zone of the Enders) is forced to remain inside the Orbital Frame Jehuty to preserve his life.
After being severely burned by Kintaro, Kabal (Mortal Kombat) must now wear a breathing mask and mobile life support to remain alive.
As his new cyborg body lacks self-repair units of its own, Raiden (Metal Gear) must periodically steal fuel cells and batteries from other robots and cyborgs to recharge and heal.
Due to his small body making incapable of flying, Arpeggio (Sly Cooper) build a mechanical birdcage on wheels to help him travel.
Frank West (Dead Rising) requires the Zombrex drug to prevent from becoming a zombie himself.
Toothless (How to Train Your Dragon) needs Hiccup to stabilize his new modified tail to fly.
Like all vampires, Angel (Buffy the Vampire Slayer) must regularly ingest mammalian blood to maintain his vitality.
Glory (Buffy the Vampire Slayer) needs to periodically drain the sanity of others to maintain her own, but to also to keep Ben from gaining control.
Joshua (No Ordinary Family) requires special injections not only to retain his powers, but to stay alive.
After being severely burned on Mustafar, Anakin Skywalker/Darth Vader (Star Wars) was placed into a mobile life support unit to sustain his life.
After losing his immune system, Mason Eckhart (Mutant X) must wear synthetic skin, a white wig, and gloves to avoid infection.
Like Joshua, Dr. Dayton King (No Ordinary Family) needs the serum to keep himself alive as well as to resist the cancer he had 18 years ago.
Darien Fawkes (The Invisible Man) needs regular injections of a special counteragent or risk being driven insane by the Quicksilver in his system.
Due to a design flaw that renders her brain unable to produce enough serotonin, Max Guevara (Dark Angel) must ingest tryptophan or drink milk in order to avoid losing her powers and/or suffering violent seizures.