The user is able to deal extremely damaging attacks to the enemy dealing double the damage or causing very lethal pain or fatal wounds. Highly advanced users can take down their opponent in one attack.
Exploit weaknesses in the opponent's armor or shields.
One swift attack can damage an enemy's vital organs.
Pokémon with the Merciless ability (Pokémon); only against poisoned opponents
Sonic the Hedgehog (Sonic the Hedgehog series)
Various characters (Soul series)
Mario (Super Mario)
Most Fighters (Yu Yu Hakusho)
Goku (Dragon Ball series) uses the Kaio-ken Finish...
...to deliver a critical blow to Nappa, breaking his back and permanently crippling him.
After tiring out Vegeta during their fight, Android 18 (Dragon Ball series) was able break his arm, greatly impeding his fighting abilities.
Goku (Dragon Ball series) uses Miracle Blow to punch through Broly's stomach, reopening his childhood wound and dealing a critical blow onto him, physically and mentally.
Gohan (Dragon Ball series) uses the Soaring Dragon Strike to deliver a with a sharp hook punch to the Cell's stomach before follows up with a swift uppercut to the his chin, sending Cell reeling back and severely injuring him.
During his fight Cell, Gohan (Dragon Ball series) in his Super Saiyan 2 was able to deliver a powerful kick to his body, not only greatly injuring Cell, but also have him eventually regurgitate Android 18 and revert back to his Semi-Perfect form.
Gohan (Dragon Ball series) use his Quiet Rage to punch right through Bojack's stomach, dealing a critical blow.
Oboro (Gintama) infusing his ki into his Hakkei strike to deal a critical blow to Gintoki's meridian.
Terra's (Kingdom Hearts series ) entire fighting style is centered around this ability.
With his Critical Impact fighting style, Terra (Kingdom Hearts series) can utilize the Zantetsuken technique to perform an impossibly fast strike that deals a devastating amount of damage.
Kain (Legacy of Kain) deals a single critical strike to an opponent by using the Fury Dark Gift.
X and Zero (Mega Man X series) can use their Special Weapons to expose their opponents weakness and deal great damage to them.
Like many characters, Yoshimitsu (Soul series) can deliver attacks that critically damage their opponents.
During his first fight with Yusuke and Kuwabara, Younger Toguro (Yu Yu Hakusho) was able to land a critical blow to Kuwabara, causing him to cough blood and slamming him into a wall.
With his 100% power, Younger Toguro (Yu Yu Hakusho) was able to deliver a critical blow to Yusuke's arm and leave him writhing in pain.