Aqua (Kingdom Hearts Birth by Sleep); via Bubble Blaster Shotlock
Bubble Kirby (Kirby: Squeak Squad)
Deku Link (The Legend of Zelda: Majora's Mask)
Bubbleman (Mega Man)
Mega Man (Mega Man); via Bubble Lead
Rain (Mortal Kombat)
Pokémon who can use "Bubble" or "Bubble Beam" (Pokémon)
Wash Buckler (Skylanders) via bubble pistol
Classic Sonic using the Bubble Shield (Sonic Generations)
Wart (Super Mario Bros)
Mizutsune (Monster Hunter)
Takumi Yura (Alive: The Final Evolution) can create compressed air bubbles that serve as powerful mini-bombs.
The Bubble (Card Captor Sakura) is able to generate bubbles as she desires.
Hiyori (Code:Breaker) can create bubbles with various effects.
Eliade (D.Gray-Man) producing vast quantities of bubbles that absorb moisture from everything they hit, leaving them dried up husks.
Yokomon (Digimon) is amongst the many baby-level Digimon who spit bubbles as their main offensive attack.
Fleur Delacour (Harry Potter) creating a Bubble-Head Charm over her mouth to breathe underwater.
Caeser Zeppeli (JoJo's Bizarre Adventure Part II Battle Tendency), Bubble Launcher - Signature Attack. Caesar fires out a barrage of bubbles from his gloves, each coated in the Hamon/Ripple. This increases the density of the bubbles and are able to hit objects with a greater impact.
Josuke Higashikata (JoJo's Bizarre Adventure Part 8 JoJolion) Soft & Wet can "steal something from [an object] and take it for itself". Usually Josuke's bubbles must make contact with his target to do this.
Aqua (Kingdom Hearts Birth by Sleep) using her Bubble Blaster attack.
With Babbo Version 2 - Bubble Launcher, Ginta (Marchen Awakens Romance) can shoot bubbles that explode when they pop.
Magical Roe (Marchen Awakens Romance) can create bubbles in the shape of lions with his Nature ÄRM, Bubble Leo.
Through his bubble wand, Bubbler (Miraculous Ladybug) is able to generate an infinite number of a vast variety of giant bubbles.
Fizzy (My Little Pony 'n Friends) creating bubbles using her unicorn magic.
Utakata (Naruto) can create many types of bubbles via his bubble blower.
Because of the Awa Awa no Mi, Kalifa (One Piece) is a soap woman and can generate bubbles at will.
Bartholomew Kuma (One Piece) compressing air into a small bubble, and then releasing it as an air bomb.
Mew (Pokémon) creating a bouncy bubble out of psychic energy to cushion Ash's impact.
Piplup (Pokémon) using "Bubble Beam" to fire a beam of bubbles that can potentially slow down foes.
SpongeBob SquarePants (SpongeBob SquarePants) is famous for being able to blow bubbles in various shapes that no ordinary people can.
Welco, A.K.A. Experiment 074 (Stitch!)
The Mizutsune (Monster Hunter) can secrete a foam that produces bubbles when mixed with water.